The guidelines

Two documents now shape how clinicians treat and define myocardial infarction. This site was built to bring them within easy reach.

The collection

Two landmark documents

Written by expert panels, these set the standard of care and the shared language of myocardial infarction. Please read the originals. They are the authority.

ACC · AHA · ACEP · NAEMSP · SCAI

2025

Guideline for the Management of Patients With Acute Coronary Syndromes

Exhibit I

Rao SV, O'Donoghue ML, Ruel M, et al. 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol. 2025;85(22):2135-2237.

How to assess, treat, and follow patients with acute coronary syndromes, from the first ECG to cardiac rehabilitation, with the class and level of evidence behind every recommendation.

Watch the lecture

Read the guideline Search all 103 recommendations

ESC · ACC · AHA · WHF

2026

Fifth Universal Definition of Myocardial Infarction

Exhibit II

Mills NL, Newby LK, Zaman S, et al. Fifth Universal Definition of Myocardial Infarction (2026). Eur Heart J. 2026. Co-published in J Am Coll Cardiol, Circulation, and Glob Heart.

The shared definition of myocardial injury and infarction, now sorted into primary, secondary, and procedure-related MI, and the pathway from a troponin result to a classification.

Translate the 4th UDMI into the 5th

Read the definition Terminology UDMI classifier

Why this website exists

Great documents change practice only when people can find, read, and use them. This website was designed to increase the uptake and accessibility of these two documents among residents, fellows, and the clinicians who teach them.

Findable. Every recommendation of the 2025 guideline is on one searchable page, with its class, level of evidence, supportive text, and references.
Usable. The UDMI classifier walks the 5th UDMI pathway, and the crosswalk and ICD-11 lookup translate the older vocabulary that most guidelines and charts still use.
Teachable. The terminology pages, lectures, and probability primer explain the ideas behind the recommendations.

This site is an educational companion and does not replace the originals, local protocols, or clinical judgment.